Mercyhurst North East remained winless after the holiday break after dropping a conference road game Tuesday at Genesee.
The Cougars went ahead 42-36 at the half and the Saints could never recover in the second half as they fall to 11-4 on the year.
Soutiri Sapnas led the Saints with 28 points on 10-of-23 shooting. Damon Jones was 10-of-18 from the field on his way to 27 points. Devonte Isom hit five 3-pointers on his way to 15 points. Marquel Hillard scored 10 in defeat.
Mercyhurst will look to earn their first conference win Thursday when they travel to Jamestown Olean.