Mercyhurst lost for the first time since opening night as the Tribunes stopped the Saints high powered offense in the Saints first game since the holiday break.
Mercyhurst looked a bit rusty, shooting 42.4 percent from the floor. Damon Jones led Mercyhurst with 24 points. Soutiri Sapnas had 12 points while Quamir White added 10 in defeat.
Mercyhurst, who has been solid this season at the free throw line, made just 15-of-24 and also made only three 3-pointers in the game.
The Saints are now 11-2 on the year and will look to get back on track Saturday at Erie Community College.