In the Saints final regular season game, Bryant & Stratton edged out MNE 2-1. With the loss, the Saints will now have to travel back to Bryant for the first round of the Region III tournament.
The Cougars scored twice in the first half to take a 2-0 lead into the intermission.
Kait Levesque scored for Mercyhurst in the second half but the Saints couldn't manage another goal.
Mercyhurst finishes the regular season at 7-7 and will be back at Bryant & Stratton Wednesday for the playoffs.